Corticosteroids are one of the most common first line treatments for ITP. They help raise platelet counts by calming the immune system and reducing platelet destruction. Steroids often work quickly, which is why they are used when a fast response is needed.
Corticosteroids are usually the first treatment offered when someone needs help raising their platelet count. They may be used when:
Steroids are generally used for short periods to avoid long term side effects.
Corticosteroids work in several ways to help increase platelet counts.
They suppress parts of the immune system, which reduces the production of antibodies that target platelets. They also help reduce inflammation, which can stabilise blood vessels and lower the risk of bleeding. In addition, corticosteroids slow the destruction of platelets in the spleen and other parts of the immune system.
Together, these effects allow platelet counts to rise, often within days.
Side effects depend on the dose and how long the treatment is used.
Common effects include:
Long term use is avoided because of risks such as:
Most side effects improve once treatment stops.
These points help patients understand the practical side of steroid treatment:
